Any mRNA purchased from RIBOPRO can be formulated into lipid nano particles (LNPs) either with lipids being supplied by our customers or our proprietary lipids.
Our specialty is to formulate RNA in LNPs using the proprietary lipids and the unique formulation technology we develop at RIBOPRO.
Request LNP formulationOur specialty is formulation in LNPs using the proprietary lipids and the unique microfluidic system we develop at RIBOPRO. Our LNPs display high mRNA delivery efficiency with low toxicity and immunogenicity, which is ideal for therapeutic use.
By using a novel core lipid system, our LNPs show a substantially lower bio-distribution to the liver, allowing the (active) targeting towards other organs. The ionizable lipids we developed have an extraordinary low toxicity and immunogenicity, while having a reasonably high endosomal escape activity.
Our services include:
When ordering custom mRNA-LNP formulation, you have various choices and options to customize the product to your exact needs. Is your favorite option not listed? Please contact us and we are happy to discuss a custom project with you.
| Choice | Description |
| Formulation | We have a list of standard LNP formulations ready to use based on your application. |
| Target delivery | We can co-develop target delivery LNPs using our proprietary lipids. |
| Buffer | Phosphate pH6-8, standard pH7.4 Citrate pH4-6 MES pH5.5-6.5 HEPES pH7-8 Other buffer upon request |
| Sterile filtering | 0.22um (recommended) 0.45um |
| QC assays | Zèta-potential by DLS Surface-charge by TNS RNA-encapsulation by RiboGreen |
Ready to take the next step? Getting a quote from us is quick and easy! Follow these simple steps to receive your personalized quote:
Fill out the form below and get your personalized quote today. If you prefer, you can also schedule a meeting with one of our Product Specialists. We’re excited to work with you!
